Vuyo Jack grew up in Dube, Soweto where he toyed with the idea of becoming a film director, before a family friend in merchant banking changed his mind. He then decided to study accounting which he sees as a critical basis for informed economic decision-making, in the sense that it is the central measure of business performance. He holds a BCom from Wits University and is a chartered accountant. Since co-founding Empowerdex, Vuyo was appointed as a member of the dti's BEE Task Team in 2003 and has advised both government departments as well as various corporates on matters of BEE.

A director of various companies including the Public Investment Corporation, Vuyo was also appointed by the minister of finance as a commissioner on the Davis tax review committee. He was nominated as a Young Global Leader by the 2009 World Economic Forum.